KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPTOR
All Species:
28.48
Human Site:
S1218
Identified Species:
56.97
UniProt:
Q8N122
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N122
NP_065812.1
1335
149038
S1218
T
A
W
V
V
K
A
S
L
Q
K
R
P
D
G
Chimpanzee
Pan troglodytes
XP_001161716
1335
149161
S1218
T
A
W
V
V
K
A
S
L
Q
K
R
P
D
G
Rhesus Macaque
Macaca mulatta
XP_001110471
1335
148870
S1218
T
A
W
V
V
K
A
S
L
Q
K
R
P
D
G
Dog
Lupus familis
XP_850487
1335
149172
Y1218
T
A
W
V
V
K
A
Y
L
Q
K
H
P
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q0
1335
149453
Y1218
T
A
W
V
V
K
A
Y
L
Q
K
H
P
E
G
Rat
Rattus norvegicus
NP_001127971
1335
149475
Y1218
T
A
W
V
V
K
A
Y
L
Q
K
H
P
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426232
1335
149895
Y1218
T
A
W
V
V
K
A
Y
L
Q
K
H
P
E
G
Frog
Xenopus laevis
NP_001088177
1334
149513
Y1217
S
A
W
V
I
K
T
Y
L
Q
K
Q
S
D
G
Zebra Danio
Brachydanio rerio
XP_001919288
1332
149175
H1215
G
A
W
V
V
K
A
H
L
Q
K
E
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624060
1279
144157
G1163
E
H
T
A
W
V
L
G
T
S
L
R
K
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323654
1366
149968
P1248
V
V
G
I
G
F
Q
P
G
L
D
P
G
K
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38873
1557
177591
W1404
G
N
D
K
Q
G
V
W
I
N
N
V
H
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
95.9
N.A.
96.5
96.7
N.A.
N.A.
95
90.5
87.9
N.A.
N.A.
55.5
N.A.
N.A.
Protein Similarity:
100
99.5
99.1
98.3
N.A.
98.4
98.5
N.A.
N.A.
97.6
95.9
94.6
N.A.
N.A.
70.4
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
80
60
73.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
80
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
40.8
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
58.2
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
0
9
0
0
67
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
9
0
0
34
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
9
0
42
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
9
0
9
9
0
9
9
0
0
0
9
0
75
% G
% His:
0
9
0
0
0
0
0
9
0
0
0
34
9
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
75
0
0
0
0
75
0
9
9
0
% K
% Leu:
0
0
0
0
0
0
9
0
75
9
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
9
67
0
0
% P
% Gln:
0
0
0
0
9
0
9
0
0
75
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
25
0
9
0
0
9
0
0
% S
% Thr:
59
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
9
9
0
75
67
9
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
75
0
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _